Trey Ideker

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• B.A. magna cum laude in Biochemistry Harvard University, Cambridge, MA. 1975
• M.Eng. in Electrical Engineering and Computer Science, M.I.T. 1995
• Ph.D. in Molecular Biotechnology, University of Washington 2001

Trey Ideker, Ph. D. is Associate Professor of Bioengineering at UC San Diego, Adjunct Professor of Computer Science, and Member of the Moores UCSD Cancer Center. He received predoctoral degrees from MIT in Electrical Engineering and Computer Science and his Ph.D. from the University of Washington in Molecular Biology under the supervision of Dr. Leroy Hood. Ideker is a pioneer in using genome-scale measurements to construct network models of cellular processes and disease. His recent research activities include development of software and algorithms for protein network analysis, network-level comparison of pathogens, and genome-scale models of the response to DNA-damaging agents. His work has been featured recently in the Scientist, Technology Review, the San Diego Union Tribune, and Forbes magazine.

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Chris Sander

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• B.A. University of Berlin, Germany
• Ph.D University of California at Berkeley, CA

The primary research interests of the Sander Group are in computational and systems biology, including predictive simulations of biological processes, integrated molecular profiling of disease states, gene regulation by small RNAs, structural genomics and the development of multiplex cancer therapy. In addition, the Sander Group leads community efforts to create an open-source information resource for biological pathways.

Current areas of research in the Sander group include: identification of oncogenically altered pathways from genomic and molecular profiling in cancer, algorithms for the analysis of cancer genomics data, design of combinatorial cancer therapy, drug target identification, knowledge representation of biological pathways, protein evolution, specificity in protein networks, and the function of small RNAs.

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Owen White

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• B.A. Biotechnology, University of Massachusetts, Amherst, MA 1985
• Ph.D. Molecular Biology, New Mexico State University, Las Cruces, NM , 1992

Dr. White has overseen the annotation of hundreds of genomes sequenced using computer analyses such as pairwise searches, multiple sequence alignments, and numerous other methods in combination with systematic manual evaluation. This administration of analysis has served to generate highly uniform annotation that includes the genomes for Arabidopsis, the mosquito Aedes agypti, parasitic organisms such as Trypanosoma Brucei and Plasmodium falciparum, human ESTs and many Bacterial and Archaeal species. He has also developed automated annotation systems such as TIGRFams (http://www.tigr.org/TIGRFAMs), Genome Properties (http://www.tigr.org/Genome_Properties), as well as the Annotation Engine (http://ae.igs.umaryland.edu/).

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Stephen Wong

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• B.E. University of Western Australia, Perth, AU
• M.S. Lehigh University, Bethlehem, PA
• Ph.D. Lehigh University, Bethlehem, PA

Stephen Wong, Ph.D., P.E. was recruited to head up Bioinformatics for the Methodist Hospital Research Institute in May of 2007. He also serves as Chief of Medical Physics and Vice Chairman of Radiology for The Methodist Hospital. Dr. Wong is the former Director of the Center for Bioinformatics, Harvard Center of Neurodegeneration and Repair (HCNR), founding Executive Director of Functional and Molecular Imaging Center, Department of Radiology, Brigham and Women's Hospital, and Associate Professor of Radiology, Harvard Medical School. His research theme has been focused on the application of advanced technology to pragmatic biomedical problems and is based on the belief that problems of importance involve the interplay between theory and application. His research interest is to solve neurological and oncological problems via multi-scale bioimaging, biosensing, and systems biology methods.

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